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The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
2-phospho-D-glycerate hydro-lyase; alpha enolase like 1; Alpha-enolase; alpha-enolase; c-myc promoter-binding protein-1; CD49 antigen-like family member E; Cd49e; C-myc promoter-binding protein; ENO1; ENO1L1; Enolase 1; enolase 1, (alpha); enolase-alpha; epididymis secretory protein Li 17; fibronectin receptor alpha polypeptide; fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; FNRA; HEL-S-17; integrin alpha 5; integrin alpha 5 (fibronectin receptor alpha); integrin alpha-5; Integrin alpha-5 heavy chain; Integrin alpha-5 light chain; Integrin alpha-F; integrin subunit alpha 5; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); ITGA5; Itga5_retired; MBP-1; MBPB1; MPB1; MPB-1; MYC promoter-binding protein 1; NNE; Non-neural enolase; phosphopyruvate hydratase; Plasminogen-binding protein; PPH; tau-crystallin; very late activation protein 5, alpha subunit; VLA5; VLA-5; VLA5A
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